"In a comprehensive time-series analysis, Nevison (2014) examined temporal trends in U.S. autism prevalence from 1970 to 2005 and correlated them with environmental exposure data. She found that the most strongly correlated factors were: Polybrominated diphenyl ethers (PBDEs), Aluminum adjuvants, and Glyphosate, the active ingredient in Roundup.
These exposures rose in parallel with autism prevalence—and many (like aluminum) were present in pediatric vaccines. Nevison did not claim causality, but emphasized the need to consider multiple low-level environmental exposures as co-factors in ASD development."
That’s a cogent summary, Greg. I believe that the greatest determinant of causality is the simultaneous in crease in body burden and outcome. In fact, that’s what tipped the balance for Grok.
From a public health perspective that’s enough for me to make the call to remove Glyphosate. As you noted it’s not the only factor but it’s probably the most significant.
Thank you Jen. I have re-read the Wakefield paper. As a result I have revised the text accordingly:
"Wakefield et al. based their paper on a study of 12 children and asserted that the MMR vaccine itself was the causative agent a claim which proved to have no basis. As a result the Wakefield paper was retracted. Other investigators asserted that the Ethylmercury containing preservative Thimerosal was the culprit. Thimerosal was subsequently removed from vaccines in 2001."
I think the exposure timing needs to be investigated further. Many parents report dramatic changes in their child very shortly after vaccination. I don't know what proportion of overall diagnoses fall into this category, but if it is significant, it is obviously at odds with the cumulative exposure to glyphosate and its metabolites hypothesis.
Your comment caused me to spend a lot of time with Grok exploring a number of alternatives for the sudden increase in rate of Autism. I'm going to publish the results only as a note. I think that you may be as surprised as I was at the final conclusion. But then I wasn't all that surprised.
Very interesting.
I thought so as well.
When I read your post I thought of the 2014 Nevison study discussed by J.B. Handley in his 2017 book "How to End the Autism Epidemic":
Today, I just read a post by James Lyons-Weiler summarizing the science between vaccines and autism: https://popularrationalism.substack.com/p/johns-hopkins-continues-to-mislead In it, he mentions the Nevison study:
"In a comprehensive time-series analysis, Nevison (2014) examined temporal trends in U.S. autism prevalence from 1970 to 2005 and correlated them with environmental exposure data. She found that the most strongly correlated factors were: Polybrominated diphenyl ethers (PBDEs), Aluminum adjuvants, and Glyphosate, the active ingredient in Roundup.
These exposures rose in parallel with autism prevalence—and many (like aluminum) were present in pediatric vaccines. Nevison did not claim causality, but emphasized the need to consider multiple low-level environmental exposures as co-factors in ASD development."
That’s a cogent summary, Greg. I believe that the greatest determinant of causality is the simultaneous in crease in body burden and outcome. In fact, that’s what tipped the balance for Grok.
From a public health perspective that’s enough for me to make the call to remove Glyphosate. As you noted it’s not the only factor but it’s probably the most significant.
Thanks for your input!
Please re read Wakefield’s paper. It was not about Thimerosal. Rather it mentioned the MMR exposure reported by the parents.
Thank you Jen. I have re-read the Wakefield paper. As a result I have revised the text accordingly:
"Wakefield et al. based their paper on a study of 12 children and asserted that the MMR vaccine itself was the causative agent a claim which proved to have no basis. As a result the Wakefield paper was retracted. Other investigators asserted that the Ethylmercury containing preservative Thimerosal was the culprit. Thimerosal was subsequently removed from vaccines in 2001."
Thank you for bringing that to my attention!
I think the exposure timing needs to be investigated further. Many parents report dramatic changes in their child very shortly after vaccination. I don't know what proportion of overall diagnoses fall into this category, but if it is significant, it is obviously at odds with the cumulative exposure to glyphosate and its metabolites hypothesis.
Your comment caused me to spend a lot of time with Grok exploring a number of alternatives for the sudden increase in rate of Autism. I'm going to publish the results only as a note. I think that you may be as surprised as I was at the final conclusion. But then I wasn't all that surprised.